Amy Rudd represents clients in a range of industries, including pharmaceutical products, financial services, healthcare and insurance, among others, in complex, multi-jurisdictional litigation matters. She has also counseled clients before regulatory boards around the world, including the Federal Energy Regulatory Commission and the International Trade Commission.

Rudd also maintains an extensive pro bono practice. Her work includes the successful representation of the Texas NAACP and the Mexican American Legislative Caucus in a bench trial and appellate briefing against Texas' voter ID law in 2016.