Manuel López-Zambrana ("Nolin") represents clients in a variety of industries such as financial, mutual funds, manufacturing, not for-profit, insurance airline transportation, maritime transportation and telecommunications industries. Nolin's expertise is highly sought after in all stages of tax controversies. He is considered by Chambers and Partners publication as a "standout tax practitioner who receives glowing recommendations from sources as one of the leading lawyers in the field." Nolin also advises clients on complex US federal and PR income tax matters and assists them with obtaining PR tax incentives for manufacturing and IP licensing activities (Act 73-2008), qualified energy activities (Act 83-2010), export services and foreign trade activities (Act 20-2012), individual resident investors (Act 22-2012), among others.

Nolin has also served as advisor to the Puerto Rico Department of the Treasury and to the Government Development Bank for Puerto Rico. He was capital member of various major law firms in Puerto Rico and is a frequent speaker at numerous seminars and conferences sponsored by the Puerto Rico State Society of Certified Public Accountants, Puerto Rico Chamber of Commerce, the Puerto Rico Manufacturers Association and other professional organizations.