Loren Brown serves as US Vice-Chairman, Chair of the Disputes Practice, and a member of the Global Board and US Executive Committee.

Loren has an extensive litigation practice with a concentration in multi-district litigation that often involves large-scale mass tort and class action matters, as well as parallel regulatory and government enforcement proceedings.

Loren has served as national coordinating counsel, tried jury cases, argued appeals and successfully resolved many notable multi-district litigation matters throughout the US.  Recent examples include multi-district litigation involving the Cox-2 anti-inflammatory medications Celebrex and Bextra, the smoking cessation medication Chantix, the hormone therapies Premarin and Prempro, the diabetes medication Victoza, the testosterone therapy Depo-T, the cholesterol-lowering medication Lipitor, and the blood thinner Eliquis.

Loren's business litigation practice includes a range of commercial tort and contract, trade secret, intellectual property and securities class action matters. Loren also has significant experience in a range of internal investigation, compliance, and regulatory matters, particularly within the life sciences sector.

Loren also regularly counsels clients on a wide-range of regulatory, risk management, due-diligence, product labeling, product recall, public disclosure, policy and crisis-management issues.

Loren also speaks and writes frequently on the subjects of multi-district litigation, expert evidence, mass tort and product liability litigation, risk mitigation and prevention, pharmaceutical and medical device litigation, and civil trial practice.

Chambers USA has recognized Loren as a national leader in the product liability and pharmaceutical litigation areas who is "particularly lauded for his deep technical expertise in this field." Sources have called him "an excellent trial lawyer," and clients have said Loren is "agile with the facts and gives great strategic advice" and added that he is "also earning accolades for his soft skills and general litigation expertise." "There is usually a difference between the attorneys who try cases and those who shape the law. There are a few who do both. Loren is one of them," stated another client. The directory added that commentators have described him as "an expert trial lawyer and as strong as they get for overall strategy." Additionally, he has been "identified for his 'deep expertise in the scientific issues on a product liability claim' and considered 'a tremendous resource for the client.'"

The Legal 500 United States also has recognized Loren as "outstanding" and a "key selling point" in the firm’s mass tort and pharmaceutical litigation practices. The directory has called him a "highly regarded life sciences expert" who is held in the "highest regard" by peers and a seasoned litigator "whose expertise clients value highly." Furthermore, it noted that he has "an excellent scientific mind," "thinks through things from new angles" and is "very good on case strategy."

In 2021, the New York Law Journal named Loren to its Distinguished Leaders list recognizing lawyers in leadership roles who achieved impressive results over the past year and "had great performances while demonstrating clear leadership skills leading to positive outcomes." Loren was named to the National Law Journal's prestigious list of Litigation Trailblazers in 2016 and to BTI Consulting Group's exclusive list of Client Services All-Stars in 2017. In 2008, he was honored by Pfizer with it's first-ever Lawyer of the Year award, in recognition of his litigation and counseling roles for that client. In 2007, American Lawyer magazine named Loren to its "Fab Fifty" list of the 50 rising litigators in the US younger than 45. Loren is also regularly named a New York Super Lawyer in the area of civil litigation and is listed in Euromoney's Guide to the World's Leading Product Liability Lawyers.